Home › Large (250–399 CADR)

Best Large (250–399 CADR) Air Purifiers

Open living areas up to about 600 sq ft. 18 ranked by overall score; the top three are the picks for most people.

Updated October 18, 2026. Best value in this class: Dreo Macro Pro. Cheapest: Dreo Macro Pro at $130.

Dreo Macro Pro

#1 of 18 in large

$130

4.1

258 cfmsmoke CADR

400 sq ftAHAM room size

53 dBat full speed

40 Wmax power

Value Quietness Filter cost

Strong CADR per dollar with app and auto mode; very quiet on low.

One air change of a 300 sq ft room in about 9 min$100 a year in filters$630 to own for 5 yearsAHAM Verifide CADR

Amazon · $130 Dreo Full review

Levoit Core 400S

#2 of 18 in large · independently tested

$180

3.8

260 cfmsmoke CADR

403 sq ftAHAM room size

52 dBat full speed

38 Wmax power

Value Quietness Filter cost

Very efficient CADR per watt; filters are rated for only six months.

One air change of a 300 sq ft room in about 9 min$100 a year in filters$680 to own for 5 yearsAHAM Verifide CADR

Amazon · $180 Levoit Full review

Blueair Blue Pure 311 Auto

#3 of 18 in large

$200

3.7

250 cfmsmoke CADR

388 sq ftAHAM room size

50 dBat full speed

30 Wmax power

Value Quietness Filter cost

Efficient medium-room unit; superseded by the 311i Max.

One air change of a 300 sq ft room in about 10 min$120 a year in filters$800 to own for 5 yearsAHAM Verifide CADR

Amazon · $200 Blueair Full review

Blueair Blue Pure 311i Max

#4 of 18 in large · independently tested

$170

3.7

250 cfmsmoke CADR

388 sq ftAHAM room size

50 dBat full speed

36 Wmax power

Value Quietness Filter cost

Medium-room Blueair with very low power draw and app.

One air change of a 300 sq ft room in about 10 min$120 a year in filters$770 to own for 5 yearsAHAM Verifide CADR

Amazon · $170 Blueair Full review

Levoit EverestAir

#5 of 18 in large · independently tested

$400

3.7

360 cfmsmoke CADR

558 sq ftAHAM room size

52 dBat full speed

49 Wmax power

Value Quietness Filter cost

Levoit's flagship with a laser sensor and directional vent; expensive for the CADR.

One air change of a 300 sq ft room in about 7 min$160 a year in filters$1,200 to own for 5 yearsAHAM Verifide CADR

Amazon · $400 Levoit Full review

Coway Airmega 300

#6 of 18 in large

$279

3.6

300 cfmsmoke CADR

465 sq ftAHAM room size

52 dBat full speed

57 Wmax power

Value Quietness Filter cost

Two-sided filtration with a real carbon layer; filters cost more than most.

One air change of a 300 sq ft room in about 8 min$110 a year in filters$829 to own for 5 yearsAHAM Verifide CADR1.1 lb activated carbon

Amazon · $279 Coway Full review

Coway Airmega 400

#7 of 18 in large

$379

3.5

350 cfmsmoke CADR

542 sq ftAHAM room size

52 dBat full speed

66 Wmax power

Value Quietness Filter cost

High CADR at a quiet 52 dB maximum; annual filter cost is among the highest here.

One air change of a 300 sq ft room in about 7 min$130 a year in filters$1,029 to own for 5 yearsAHAM Verifide CADR1.3 lb activated carbon

Amazon · $379 Coway Full review

Alen BreatheSmart 75i

#8 of 18 in large · independently tested

$599

3.4

347 cfmsmoke CADR

538 sq ftAHAM room size

49 dBat full speed

60 Wmax power

Value Quietness Filter cost

Quiet at full speed and well built; price per CADR is high.

One air change of a 300 sq ft room in about 7 min$99 a year in filters$1,094 to own for 5 yearsAHAM Verifide CADR

Amazon · $599 Alen Full review

Coway Airmega 400S

#9 of 18 in large

$449

3.4

350 cfmsmoke CADR

542 sq ftAHAM room size

52 dBat full speed

66 Wmax power

Value Quietness Filter cost

Airmega 400 with Wi-Fi app control.

One air change of a 300 sq ft room in about 7 min$130 a year in filters$1,099 to own for 5 yearsAHAM Verifide CADR1.3 lb activated carbon

Amazon · $449 Coway Full review

Blueair Blue Pure 211+ Auto

#10 of 18 in large · independently tested

$280

3.4

350 cfmsmoke CADR

542 sq ftAHAM room size

56 dBat full speed

61 Wmax power

Value Quietness Filter cost

211+ with a particle sensor and auto mode.

One air change of a 300 sq ft room in about 7 min$140 a year in filters$980 to own for 5 yearsAHAM Verifide CADR

Amazon · $280 Blueair Full review

Blueair Blue Pure 211+

#11 of 18 in large · independently tested

$250

3.4

350 cfmsmoke CADR

542 sq ftAHAM room size

56 dBat full speed

61 Wmax power

Value Quietness Filter cost

High CADR, simple one-button operation, fabric prefilter; no auto mode and short filter life.

One air change of a 300 sq ft room in about 7 min$140 a year in filters$950 to own for 5 yearsAHAM Verifide CADR

Amazon · $250 Blueair Full review

Honeywell HPA5300

#12 of 18 in large

$250

3.2

300 cfmsmoke CADR

465 sq ftAHAM room size

58 dBat full speed

120 Wmax power

Value Quietness Filter cost

HPA300 internals with a particle sensor, auto mode and app.

One air change of a 300 sq ft room in about 8 min$60 a year in filters$550 to own for 5 yearsAHAM Verifide CADR

Amazon · $250 Honeywell Full review

Honeywell HPA300

#13 of 18 in large · independently tested

$190

3.2

300 cfmsmoke CADR

465 sq ftAHAM room size

60 dBat full speed

130 Wmax power

Value Quietness Filter cost

Proven large-room CADR at a fair price; loud and power-hungry at full speed, no auto mode.

One air change of a 300 sq ft room in about 8 min$60 a year in filters$490 to own for 5 yearsAHAM Verifide CADR

Amazon · $190 Honeywell Full review

Winix T810

#14 of 18 in large · independently tested

$249

3.1

267 cfmsmoke CADR

414 sq ftAHAM room size

62 dBat full speed

45 Wmax power

Value Quietness Filter cost

Winix publishes a 267 dust CADR (343 sq ft at 5 air changes); smoke and pollen figures are not published, so dust is used for all three. App control and a heavy carbon filter at a mid-range price.

One air change of a 300 sq ft room in about 9 min$90 a year in filters$699 to own for 5 yearsAHAM Verifide CADR1.2 lb activated carbon

Amazon · $249 Winix Full review

Medify MA-40

#15 of 18 in large · independently tested

$170

3.1

330 cfmsmoke CADR

512 sq ftAHAM room size

56 dBat full speed

68 Wmax power

Value Quietness Filter cost

High claimed CADR for the money; not AHAM listed, and filters are short-lived.

One air change of a 300 sq ft room in about 7 min$160 a year in filters$970 to own for 5 years

Amazon · $170 Medify Full review

Rabbit Air A3

#16 of 18 in large

$600

3.0

262 cfmsmoke CADR

406 sq ftAHAM room size

51 dBat full speed

57 Wmax power

Value Quietness Filter cost

Rabbit Air's larger unit with app and a laser sensor; premium price.

One air change of a 300 sq ft room in about 9 min$100 a year in filters$1,100 to own for 5 yearsAHAM Verifide CADR

Amazon · $600 Rabbit Air Full review

Blueair HealthProtect 7470i

#17 of 18 in large

$550

2.6

300 cfmsmoke CADR

465 sq ftAHAM room size

51 dBat full speed

55 Wmax power

Value Quietness Filter cost

Premium build and very quiet low speed; CADR per dollar is poor.

One air change of a 300 sq ft room in about 8 min$240 a year in filters$1,750 to own for 5 yearsAHAM Verifide CADR

Amazon · $550 Blueair Full review

Mila Air Purifier

#18 of 18 in large · independently tested

$299

2.6

263 cfmsmoke CADR

408 sq ftAHAM room size

55 dBat full speed

55 Wmax power

Value Quietness Filter cost

Sensor-heavy smart unit with swappable filter types; filters are expensive.

One air change of a 300 sq ft room in about 9 min$198 a year in filters$1,289 to own for 5 yearsAHAM Verifide CADR

Amazon · $299 Mila Full review

Every spec, side by side

#	Model	Smoke CADR	Dust	Pollen	W	dB max	Filters/yr	$/CADR	Score
1	Dreo Macro Pro	258	260	258	40	53	$100	0.5	4.1
2	Levoit Core 400S	260	242	250	38	52	$100	0.7	3.8
3	Blueair Blue Pure 311 Auto	250	250	250	30	50	$120	0.8	3.7
4	Blueair Blue Pure 311i Max	250	321	250	36	50	$120	0.7	3.7
5	Levoit EverestAir	360	340	350	49	52	$160	1.1	3.7
6	Coway Airmega 300	300	300	300	57	52	$110	0.9	3.6
7	Coway Airmega 400	350	350	350	66	52	$130	1.1	3.5
8	Alen BreatheSmart 75i	347	350	350	60	49	$99	1.7	3.4
9	Coway Airmega 400S	350	350	350	66	52	$130	1.3	3.4
10	Blueair Blue Pure 211+ Auto	350	350	350	61	56	$140	0.8	3.4
11	Blueair Blue Pure 211+	350	350	350	61	56	$140	0.7	3.4
12	Honeywell HPA5300	300	320	300	120	58	$60	0.8	3.2
13	Honeywell HPA300	300	320	300	130	60	$60	0.6	3.2
14	Winix T810	267	267	267	45	62	$90	0.9	3.1
15	Medify MA-40	330	330	330	68	56	$160	0.5	3.1
16	Rabbit Air A3	262	270	265	57	51	$100	2.3	3.0
17	Blueair HealthProtect 7470i	300	300	300	55	51	$240	1.8	2.6
18	Mila Air Purifier	263	270	265	55	55	$198	1.1	2.6

Other room-size classes

Compact (under 130 CADR)Medium (130–249 CADR)Extra Large (400+ CADR)